Description
Why Argo?
– Bioavailability: Argo is more bioavailable than L-Glutamine and maybe more efficiently absorbed [5,6,7].
– Solubility and Stability: Argo is freely soluble and clever in water. Argo is stable in liquids and with other nutrients in varies formulation.
– L-Glutamine: Glutamine is the most abundant free amino acid in the body. Amino acids are the building blocks of protein. Glutamine is produced in the muscles and is distributed by the blood to the organs that need it. Glutamine might help gut function, the immune system, and other essential processes in the body, especially in times of stress. It is also important for providing “fuel” (nitrogen and carbon) to many different cells in the body. Glutamine is needed to make other chemicals in the body such as other amino acids and glucose (sugar).
How Argo works on your Cell?
– Alanylglutamine is absorbed by Pept-1 dipeptide transporter in the intestines and colon [2,3,4]. According to clinical trial [5], human under fasted conditions, Alanylglutamine is better absorbed than equivalent.
– Alanylglutamine appears to be more metabolized by the kidney than the liver when compared to the free amino acids, which are heavily metabolized by the liver.
– Several papers have indicated that glutamine is a preferred fuel for the enterocyte and that it can increase intestinal epithelial cell proliferation.
How is Argo Produced?
Argo is manufactured in a strictly GMP facility with highly implemented quality control and quality assurance procedure to ensure the purity of the Argo. Argo is a highly stable, water soluble product with more bioavailable than L-Glutamine alone. Argo is allergen-free, vegetarian, tasteless, odorless which makes Argo a great ingredients choice for food, drink, dietary supplements formulated to support cell nutrition and enhance body performance.
Reference
[2] Adibi S.A. The oligopeptide transporter (Pept-1) in human intestine: biology and function, Gastroenterology. 1997 Jul; 113(1):332-40.
[3] Alteheld B. et al. Alanylglutamine dipeptide and growth hormone maintain PepT1-mediated transport in oxidatively stressed Caco-2 cells, J Nutr. 2005 Jan;135(1):19-26.
[4] Ford. D. et al. Expression of the peptide transporter hPepT1 in human colon: a potential route for colonic protein nitrogen and drug absorption. Histochem Cell Biol. 2003 Jan;119(1):37-43. Epub 2002 Dec 10.
[5] Harris R.C. et al. L-glutamine absorption is enhanced after ingestion of L-alanylglutamine compared with the free amino acid or wheat protein. Nutr Res. 2012 Apr;32(4):272-7.
[6]Lima A. A. et al. Effects of an alanyl-glutamine-based oral rehydration and nutrition therapy solution on electrolyte and water absorption in a rat model of secretory diarrhea induced by cholera toxin. Nutrition. 2002 Jun;18(6):458-62.
[7]Thwaites D. T. et al. H/dipeptide absorption across the human intestinal epithelium is controlled indirectly via a functional Na/H exchanger. Gastroenterology. 2002 May;122(5):1322-33.
